The purpose of this study is to determine the effect of oral vitamin C supplements on blood sugar and serum lipid level(total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein)in non-insulin independent diabetes mellitus
The study design was a non equivalent control group pre-test post-test design. Data for the study were collected from June 24 to August 31. 2001. The ninty-five research subject were assigned to experimental group(51) and control group(44).
Vitamin C(3g/day) was given to 51 subjects for 4 weeks. Following a 12h overnight fasting, blood sample was obstaind at baseline and at the end of 4week-supplementation. Blood samples were taken for plasma vitamin C concentration, fasting blood sugar HbAlc and serum lipid level.
The pre-equivalent test was used by Chi-squre t-test and two group's pre and post experimental differences were analyzed by t-test to compare with each other.
The results of this study were as follows:
1. The difference between the two groups in plasma vitamin C concentration was signigicant (t=-12.950, p=.000).
2. The difference between the two groups in fasting blood sugar was significant(t=5.293, p=.000).
3. The difference between the two groups in HbAlc was not significant(t=1.758, p=.082).
4. The difference between the two groups in total cholesterol, HDL, LDL was signigicant (t=3.786, p=.000 ; t=-5.515 p=.000 t=4.169 p=.000)
These results suggest that megadose vitamin C supplementation be effective in lowering fasting blood sugar serum lipids and increasing plasma vitamin C. Thus dietary measures to increase plasma vitamin C may be on important health strategy for reducing the compliance of diabetic patients
|